GAT-B 2021

GAT-B - Syllabus

Graduate Aptitude Test of Biotechnology

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GAT-B 2023 Syllabus: Complete Guide for Biotechnology PG Program Admission

Updated On - May 08 2023 by Abhinandan Singh

The Graduate Aptitude Test-Biotechnology (GAT-B) 2023 is conducted for admission in various DBT supported PG programs in Biotechnology and allied areas. The GAT-B 2023 exam is conducted at the national level annually by the National Testing Agency (NTA). The GAT-B 2023 Syllabus includes topics such as Molecular Biology and Genetics, Recombinant DNA Technology, Immunology, Biochemistry, Bioinformatics, etc. The syllabus is designed to test the conceptual understanding and knowledge of candidates in the field of Biotechnology. Candidates must thoroughly prepare for the exam as it is highly competitive and admission to PG programs is based on GAT-B scores.

GAT-B 2023 Syllabus

Candidates should study the GAT-B 2023 syllabus while preparing for the entrance exam. Candidates can learn about the topics, units, and chapters from which questions will be asked in the entrance exam by consulting the GAT-B syllabus 2023. The GAT-B 2023 syllabus is available below for candidates to review.

  • Part A contains questions from the 12th grade in physics, chemistry, math, and biology.
  • Part B covers graduation-level problems in Biology, Life Sciences, Biotechnology, and related fields
GAT B Syallbus 2023
CategoryTopics Covered in GAT-B 2023 Exam
GeneralMathematics, Aptitude, General Biotechnology
Core BiotechMicrobiology, Biochemistry, Molecular Biology, etc.
The GAT-B 2023 exam syllabus covers a wide range of topics related to biotechnology, including general biotechnology, mathematics, aptitude, microbiology, biochemistry, and molecular biology. The exam is divided into two categories: general and core biotechnology. The general category focuses on fundamental concepts and principles, while the core biotechnology category delves deeper into specific subjects such as microbiology and biochemistry. Candidates should thoroughly review the syllabus before beginning their exam preparation to ensure that they cover all of the necessary topics. The GAT-B exam is a computer-based test that lasts for three hours and is held for admission to postgraduate programs in biotechnology and allied areas at participating institutions.

GAT-B 2023 exam syllabus

The syllabus includes:

Basic biology, life sciences, biotechnology and allied area: Unit 01
Structure and functions; biological membranes, structure, action potential and transport processes; enzymes-classification, kinetics, and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids)
Photosynthesis, respiration, and electron transport chain; bioenergetics
Basic biology, life sciences, biotechnology and allied area: Unit 02
Structure and classification; microbial classification and diversity (bacterial, algal, and fungal); Methods in microbiology; microbial growth and nutrition; aerobic and anaerobic respiration; nitrogen fixation
Microbial diseases and host-pathogen interaction
Basic biology, life sciences, biotechnology and allied area: Unit 03
Prokaryotic and eukaryotic cell structure
Cell cycle and cell growth control; cell-cell communication, cell signalling and signal transduction
Basic biology, life sciences, biotechnology and allied area: Unit 04
Molecular structure of genes and chromosomes
Mutations and mutagenesis; nucleic acid replication, transcription, translation, and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; complementation; linkage, recombination and chromosome mapping
Extrachromosomal inheritance; microbial genetics (plasmids, transformation, transduction, conjugation); horizontal gene transfer and transposable elements; RNA interference; DNA damage and repair; chromosomal variation
Molecular basis of genetic diseases
Basic biology, life sciences, biotechnology and allied area: Unit 05
Principles of microscopy
Light, electron, fluorescent and confocal; centrifugation-high speed and ultra; principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS, NMR; principles of chromatography-ion exchange, gel filtration, hydrophobic interaction, affinity
Principles of chromatography-GC,HPLC, FPLC; electrophoresis; microarray
Basic biology, life sciences, biotechnology and allied area: Unit 06
History of immunology
Innate, humoral and cell-mediated immunity; antigen; antibody structure and function; Molecular basis of antibody diversity; synthesis of antibody and secretion; antigen-antibody reaction; complement; primary and secondary lymphoid organ
B and T cells and macrophages; major histocompatibility complex (MHC); antigen processing and presentation; polyclonal and monoclonal antibody; regulation of immune response; immune tolerance; hypersensitivity; autoimmunity; graft versus host reaction
Basic biology, life sciences, biotechnology and allied area: Unit 07
Major bioinformatics resources and search tools
Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny); data mining and analytical tools for genomic and proteomic studies
Molecular dynamics and simulations (basic concepts including force fields, protein-protein, protein-nucleic acid, protein-ligand interaction)
Basic biology, life sciences, biotechnology and allied area: Unit 08
Restriction and modification enzymes
Vectors; plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; mammalian and plant expression vectors; cDNA and genomic DNA library; gene isolation, cloning and expression; transposons and gene targeting
DNA labelling; DNA sequencing; polymerase chain reactions; DNA fingerprinting; southern and northern blotting; in-situ hybridization; RAPD, RFLP; site-directed mutagenesis; gene transfer technologies; gene therapy
Basic biology, life sciences, biotechnology and allied area: Unit 09
Regeneration of plants; Plant growth regulators and elicitors; tissue culture and cell suspension culture system: Methodology, the kinetics of growth and, nutrient optimization; production of secondary metabolites by plant suspension cultures
Hairy root culture; transgenic plants; Plant products of industrial importance
Basic biology, life sciences, biotechnology and allied area: Unit 10
Animal cell culture
Media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; kinetics of cell growth; micro and macro carrier culture; hybridoma technology; stem cell technology; animal cloning
Transgenic animals
Basic biology, life sciences, biotechnology and allied area: Unit 11
Chemical engineering principles applied to a biological system
Principle of reactor design, ideal and non-ideal multiphase bioreactors, mass and heat transfer; Rheology of fermentation fluids, aeration and agitation; media formulation and optimization; kinetics of microbial growth
Substrate utilization and product formation; sterilization of air and media; batch, fed-batch and continuous processes; various types of microbial and enzyme reactors; instrumentation control and optimization
Unit operations in solid-liquid separation and liquid-liquid extraction; Process scale-up, economics and feasibility analysis
Basic biology, life sciences, biotechnology and allied area: Unit 12
Engineering principle of bioprocessing
Upstream production and downstream; bioprocess design and development from lab to industrial scale; microbial, animal and plant cell culture platforms; production of biomass and primary/ secondary metabolites; biofuels, bioplastics, industrial enzymes
Antibiotics; large scale production and purification of recombinant proteins; industrial application of chromatographic and membrane-based bioseparation methods; immobilization of biocatalysts (enzymes and cells) for bioconversion processes
Bioremediation-aerobic and anaerobic processes for stabilization of solid/ liquid wastes
Basic biology, life sciences, biotechnology and allied area: Unit 13
Tissue culture and its application, micropropagation
Meristem culture and production of virus-free plants
Anther and microspore culture
Embryo and ovary culture
Protoplast isolation
Protoplast fusion-somatic hybrids, cybrids
Synthetic seeds
In vitro germplasm conservation
Organelle DNA, satellite-and repetitive DNAs
DNA repair
Regulation of gene expression
Recombinant DNA technology-cloning vectors, restriction enzymes, gene cloning
Methods of gene transfer in plants
Achievements and recent developments of genetic engineering in agriculture
Development of transgenics for biotic and abiotic stress tolerance, bioethics, terminator technology, nanotechnology, DNA fingerprinting, gene silencing
The detailed syllabus of GAT-B 2023 will be released by the Regional Centre for Biotechnology (RCB), Department of Biotechnology, Government of India

To get an idea about the syllabus, you check the complete syllabus of the GAT-B 2023 Entrance exam Click here 

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