GPAT - Syllabus
Graduate Pharmacy Aptitude Test
Computer Based Test
Updated On - January 15 2021 by Anusha Pachauri
Candidates can check the subjects wise GPAT 2021 Syllabus as per previous year's information bulletin mentioned below:
Check the given below table of GPAT Physical Chemistry Syllabus:
|Composition & physical states of matter||Intermolecular forces & their impact on the state of the matter. Various physical properties of matter, dipole moment, dielectric constant, Van Der Waal's equation & critical phenomenon, liquefaction of gases, aerosols.|
|Colligative Properties||The liquid state, vapour pressure, ideal & real solutions. Raoult's law, the elevation of boiling point, depression of freezing point, osmotic pressure, determination of molecular weight based on colligative properties.|
|Thermodynamics||First, second & third law of thermodynamics. Thermochemical laws, isothermic & adiabatic|
processes, reversible processes, work of expansion, heat content, enthalpy, heat capacity.
Gibb's & Helmholtz equation & chemical potential.
|Refractive index||Refractive index, specific refractivity, molar refractivity, refractometers.|
|Solution||Solubility, factors affecting solubility, solubility curves. Types of solutions, effect of co-solvency, pH & other factors on solubility. Solubility of gases in liquids, liquids in liquids, & solids in liquids, critical solution temperature, law of partitioning & its applications. Solute-solvent interactions. Expression of the concentration of pharmaceutical solutions & calculations. Molarity, molality, mole fraction & percentage expressions.|
|Electrochemistry||Properties of electrolyte solutions, electrolysis. Faraday's law of electrolysis, electron transport, electrical cell, single electrode potential, concentration cells, half-cells & half-cell potential, types of half cells, sign convention, Nernst equation, salt bridge, electromotive series, standard potential, SHE. Measuring the relative voltage of half cells, Calculation of standard potential. Reference & indicator electrodes. Standard oxidation-reduction potential.|
|Ionic equilibrium||Theory of conductivity, equivalent conductance, mobility of ions, specific conductance.|
|Kinetics||Order of reactions, derivation & internal form of rate laws, molarities of reaction,|
derivation of rate constants.
Given below is the all information related GPAT 2021 Biochemistry Syllabus:
|Cell||Revision of ultrastructure of the cell, functions of various cellular constituents. Applications of biochemical principles to the pharmacy.|
|Carbohydrates||Types of carbohydrates, their functions, digestion, & absorption. Aerobic & anaerobic oxidation with energetics. Glycogenesis, glycogenolysis, & gluconeogenesis. Hexose monophosphate shunt [HMP shunt]. Diseases associated with carbohydrate metabolism.|
|Proteins||Different types of proteins. Their functions, digestion & absorption. Denaturation & its effect on biological activity. Renaturation of proteins. Urea formation, urea cycle, creatinine formation. Transamination & deamination. Proteins as enzymes.|
|Lipids||Different types of lipids. Their functions, digestion, absorption & metabolism. (Beta-Oxidation of fatty acids with energetics. Biosynthesis of cholesterol [from acetate], adrenocorticoids, androgens, progesterone, estrogens, & bile acids / salts. Ketone bodies, their formation & biochemical significance. Diseases associated with lipid metabolism.|
|Vitamins||Definition. Classification, structures [except B12] biochemical role, sources, daily requirements, & deficiency symptoms. Vitamins as co-factors in biochemical reactions.|
|Biological oxidations & reduction||Oxidation-reduction systems in the body their role. Oxidative phosphorylation &|
Electron transport chain. Cytochromes & inhibitors of the same.
|Enzymes||Classification & their various roles. Enzyme co-factors. Enzyme kinetics. Michaelis-Menton|
equation along with its transformations. Double reciprocal plot. Factors affecting enzyme
action. Enzyme inhibition, competitive & non-competitive, & kinetics.
|Nucleic Acids||Different types of nucleic acids [NAs] & their composition. Purine & pyrimidine bases, sugars, & phosphoric acid. Nucleosides & nucleotides. Formation of NAs & their backbone. Different ways of representing DNA & RNA molecules. Physico-chemical properties of NAs. Their stability in acidic & basic solutions. Isolation, purification & identification, buoyant density, sedimentation coefficient, & Svedberg constant of NAs. De-novo biosynthesis of NAs. DNA & the Watson-Crick model & its features. DNA as the bearer of genetic information. The Central dogma of molecular genetics & the processes defined in the same. Replication of DNA. Different types of RNAs with their special features & functions. Minor or rare bases. Transcription & translation. Different post-translational modifications of proteins. Triplet codon & the codon dictionary. Mutations. An introduction to different types of mutations. Their nature & repair.|
|Hereditary diseases||Eliptocytosis, spherocytosis, HNPCC, diabetes insipidus.|
Applicants can check the GAPT Microbiology Syllabus 2021 from the given below table:
|Introduction to Microbiology||Scope and application to pharmacy field. Whittaker's Five Kingdom concept, historical|
development - biogenesis Vs. abiogenesis, Germ theory of fermentation, Germ theory of
disease, the contribution of Leeuwenhoek, Robert Koch, Jenner, Louis Pasteur and Ehrlich
|Microscopy and staining technique||The principle, ray diagram, construction, working and applications of the light compound, darkfield, phase contrast, Fluorescence & electron microscope. The concept of resolving power, Magnification power, numerical aperture and angular aperture and working distance. The principal application of oil immersion microscopy. Theory of staining, principle and technique of staining procedure - Monochrome, Gram, acid-fast, negative, capsule, endospore.|
|Biology of Microorganisms||Cultural characteristics, pure culture techniques Bacteria - Morphology and fine structure of bacteria, Nutritional requirement and type of culture media, growth and growth curve of bacteria, physical condition for growth, measurement of bacterial growth (Counting Methods), Reproduction in bacteria, genetic exchange - transformation, conjugation, and transduction, development of drug resistance by recombination and mutation, preservation of bacterial culture. Biochemical properties (sugar fermentation and IMVIC test). Pathogenesis of Staphylococcus, Mycobacterium. Salmonella Introductory study of disease-causing rickettsia, the importance of actinomycetes in antibiotic production.|
|Fungi and Viruses||Fungi:- Introduction, general characteristics, morphology, the industrial and medical|
significance of Saccharomyces Cerevisiae, Penicillium and Aspergillus, Candida Albicans,
Epidermophyton, and trichophytic.
Viruses: - Introduction, structure and general properties Bacteriophages - Lytic and
Lysogenic cycle, Epidemiological uses of Bacteriophages, human viruses - Cultivation and
Multiplication virus-host cell interaction, Pathogenesis of HIV and Prions, types of Tumor
|Aseptic Technique||The omnipresence of microorganisms, the importance of asepsis, sources of contamination and methods of prevention, Principle, construction & working of laminar airflow bench.|
|Sterilization & Disinfection||a) Concept and classification, principle and methods of sterilization, Mechanisms of cell|
b) Construction working & applications of moist heat & dry heat sterilizer, gamma
radiation sterilizer, filtration sterilizer. Indicators of sterilization, microbial death, kinetic
terms-D value, z value.
c) Terminology of chemical antimicrobial Agents, Chemical classification of different
disinfectants, characteristics of ideal disinfectants, factors affecting the action of
disinfectants, evaluation methods (RW Coeff.), Kelsey Sykes test, Chick Martin test.
|Microbial Spoilage||Types of spoilage, factors affecting the spoilage of pharmaceutical products.|
|Vaccines & Sera||Manufacturing (seed lot system) and quality control of bacterial vaccines & Toxoids (Tetanus, TAB, Cholera, BCG, DPT), Viral vaccine (Polio- Salk Sabin, Rabies, MMR, Hepatitis, Chickenpox, influenza), Antisera (diphtheria, tetanus), antiviral Antisera (rabies). Preparation of allergenic extracts & diagnostics.|
|Microbial Assay||Importance, general methods of assay of antibiotics (Cup & plate method, paper disc method, turbidometry, dilution method), methods for fungicidal & antiviral compounds, assay, microbial limit tests|
From the given below table candidates can check the GPAT Human Anatomy and Physiology Syllabus:
|Cell Physiology||Cell, Cell junctions, transport mechanisms, homeostasis, ion channels, secondary messengers.|
|Blood||Composition and functions of blood, RBC, WBC, platelets. Homeostasis, blood groups,|
mechanism of clotting. Introduction to disorders of the blood.
|Gastrointestinal tract||Structure of the gastrointestinal tract, functions of its different parts including those of liver, pancreas and gallbladder, various gastrointestinal structures and their role in the digestion and absorption of food.|
|Respiration System||Structure of respiratory organs, functions of respiration mechanism and regulation of|
respiration, respiratory volumes and vital capacity.
|Autonomic nervous system||Physiology and functions of the autonomic nervous system. Mechanism of neurohumoral|
transmission in ANS.
|Sense organs||Structure and physiology of eye (vision), ear (hearing), taste buds, nose (smell) and skin.|
|Skeletal System||Structure and function of the skeleton. Articulation and movement. Disorders of bones and|
|Central Nervous System||Functions of different parts of the brain and spinal cord. Neurohumoral transmission in the|
central nervous system, reflex action, electroencephalogram, specialized functions of the brain, cranial nerves and their functions.
|Urinary System||Various parts Structure and functions of the kidney and urinary tract. Physiology of urine|
formation and acid-base balance. Brief Introduction to disorders of the kidney.
|Endocrine Glands||Basic anatomy and physiology of pituitary, thyroid, parathyroid, adrenal glands and pancreas. Local hormones. A brief introduction to disorders of various endocrine glands.|
|Reproductive System||Various parts Structure and functions of the kidney and urinary tract. Physiology of urine|
formation and acid-base balance. Brief Introduction to disorders of the kidney.
|Cardiovascular system||Anatomy of heart and blood vessels, physiology of blood circulation, cardiac cycle, the conducting system of the heart, heart sound, electrocardiogram, blood pressure and it's regulation.|
|Lymphatic system||Composition, formation and circulation of lymph. Spleen and its functions.|
Candidates can download previous year's syllabus pdf from the given below list of the subject:
Candidates can check the books for GPAT entrance exam 2021 preparation from the given below detail:
Candidates can download the GPAT 2021 Book Recommendation Pdf to know more books name for preparation.
23 Dec 2020
30 Jan 2021
27 Feb 2021